Research Use Only

Computational consulting for nanoparticle research

Expert-led analysis for neurotoxicology, drug delivery, and environmental health research. We help researchers design better experiments and strengthen grant proposals through rigorous physics-based methodology.

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Monte Carlo Methodology

Decades of validated simulation experience applied to emerging nanoplastic challenges.

Safety-First Framework

Every analysis bounded by cellular damage thresholds. Built-in safety validation from the start.

Publication-Ready Output

Clear reports with figures, methods sections, and uncertainty quantification for your proposals.

Principal Scientist

Mihaela Cosma

Medical Physicist / Computational Modeler

Four decades of Monte Carlo simulation experience. Pioneered microdosimetry models for cancer therapy at Memorial Sloan-Kettering Cancer Center. Published in IJROBP, NATO ASI Series, and Journal of Nuclear Medicine.

Now applying cellular-level energy modeling expertise to the emerging challenge of nanoplastics in biological systems—developing frameworks to understand particle-cell interactions before they become clinical problems.

Licensed Medical Physicist (NY) Columbia University Memorial Sloan-Kettering Monte Carlo Simulation AAPM Lifetime Member

The Challenge

Nanoplastics have been detected in human brain tissue, blood, and placenta. Researchers need to understand particle-cell interactions, but wet-lab experiments are slow, expensive, and can only test limited conditions.

$100K+

Typical wet-lab study cost

6-12 mo

Time per iteration

10-20

Conditions per study

AI-Augmented Analysis

Combining proven physics methodology with modern computational approaches to deliver faster, more comprehensive research support.

Literature Synthesis

Rapid extraction of parameters and findings across thousands of publications. Comprehensive hypothesis generation grounded in existing research.

Parameter Optimization

Monte Carlo methods combined with intelligent search to explore parameter spaces that would take months to test experimentally.

Report Generation

Structured deliverables with clear methodology, limitations, and uncertainty quantification. Ready for grant appendices and publications.

Services

Expert consulting delivered as clear, actionable reports to support your research.

Mechanistic Appendix

$2,500

For grant proposals and publications

Literature-based parameter estimates
Publication-ready figures
Hypothesis generation
Methods section draft
48-72 hour delivery

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Recommended

Pilot Partner Sprint

$25-50K

8-week collaboration

Weekly working sessions
2-4 scenario analyses
Custom report templates
Experiment design support
Go/no-go criteria development

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Enterprise R&D

Custom

For pharma preclinical teams

De-risking study design
Multi-scenario modeling
Safety threshold analysis
Dedicated support
Regulatory-aware outputs

How We Work

Consultation

Understand your research goals and experimental context

Analysis

Literature review, parameter estimation, scenario modeling

Synthesis

Generate figures, hypotheses, and recommendations

Delivery

Report with clear limitations and suggested next steps

The Vision

Imagine a world where computational modeling accelerates every stage of drug discovery

Today, we provide expert consulting. Tomorrow, we're building the platform that makes physics-based nanoparticle simulation accessible to every researcher—reducing the cost of discovery while protecting what matters most: cellular safety.

Today

Expert Consulting

Tomorrow

Simulation Platform

The Goal

Democratized Discovery

Use Cases

Grant Proposal Support

Publication-quality figures, preliminary computational data, and methods sections that strengthen funding applications.

Experiment Prioritization

Identify which parameters matter most before committing to expensive wet-lab studies. Focus resources on high-impact experiments.

Organ-on-Chip Design

Model nanoparticle behavior in BBB chips, neural organoids, and barrier tissue systems before fabrication.

Preclinical Safety

Binding energy and safety threshold analysis to de-risk nanoparticle drug delivery candidates.

Ready to accelerate your research?

Whether you're writing a grant, designing experiments, or de-risking a preclinical program, we can help.

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